I was running Stage 2 tune on the 42# Stage 2 injectors with a 2.8 pulley.
I ran it for about 2 weeks and then started noticing I was getting bad knock after 6K rpm (it was leaning out because of the pulley and the injectors were too small for the 17 lbs of boost it was making.)
I had the presence of mind to order 60 lb injectors and went and got it professionally tuned. What I came away with was a nice strong, safe tune with AFRs under 12 past 2500 rpms. I even gained 3 mpg

My 42 lb injectors were at about 120% IDC. The 60 lb injectors never go above 30% IDC

Much more room to go on those with other mods.